• Kolbe, Katharina; Haffner, Ivonne; Schierle, Katrin; Maier, Dieter; Geier, Birgitta; Luber, Birgit; Bläker, Hendrik; Wittekind, Christian; Lordick, Florian: Deviating HER2 test results in gastric cancer: analysis from the prospective multicenter VARIANZ study. 149 (3), 2023, 1319-1329 mehr…
• Ebert, Karolin; Haffner, Ivonne; Zwingenberger, Gwen; Keller, Simone; Raimúndez, Elba; Geffers, Robert; Wirtz, Ralph; Barbaria, Elena; Hollerieth, Vanessa; Arnold, Rouven; Walch, Axel; Hasenauer, Jan; Maier, Dieter; Lordick, Florian; Luber, Birgit: Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies-the role of HAS2, SHB and HBEGF. 22 (1), 2022 mehr…
• Wang, Jun; Kunzke, Thomas; Prade, Verena M; Shen, Jian; Buck, Achim; Feuchtinger, Annette; Haffner, Ivonne; Luber, Birgit; Liu, Drolaiz H W; Langer, Rupert; Lordick, Florian; Sun, Na; Walch, Axel: Spatial Metabolomics Identifies Distinct Tumor-Specific Subtypes in Gastric Cancer Patients. 28 (13), 2022, 2865-2877 mehr…
• Kunzke, Thomas; Hölzl, Fabian T; Prade, Verena M; Buck, Achim; Huber, Katharina; Feuchtinger, Annette; Ebert, Karolin; Zwingenberger, Gwen; Geffers, Robert; Hauck, Stefanie M; Haffner, Ivonne; Luber, Birgit; Lordick, Florian; Walch, Axel: Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer. 11 (9), 2021 mehr…
• Haffner, Ivonne; Schierle, Katrin; Raimúndez, Elba; Geier, Birgitta; Maier, Dieter; Hasenauer, Jan; Luber, Birgit; Walch, Axel; Kolbe, Katharina; Riera Knorrenschild, Jorge; Kretzschmar, Albrecht; Rau, Beate; Fischer von Weikersthal, Ludwig; Ahlborn, Miriam; Siegler, Gabriele; Fuxius, Stefan; Decker, Thomas; Wittekind, Christian; Lordick, Florian: HER2 Expression, Test Deviations, and Their Impact on Survival in Metastatic Gastric Cancer: Results From the Prospective Multicenter VARIANZ Study. 39 (13), 2021, 1468-1478 mehr…
• Prade, Verena M; Kunzke, Thomas; Feuchtinger, Annette; Rohm, Maria; Luber, Birgit; Lordick, Florian; Buck, Achim; Walch, Axel: De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry. 36, 2020 mehr…
• Ebert, Karolin; Zwingenberger, Gwen; Barbaria, Elena; Keller, Simone; Heck, Corinna; Arnold, Rouven; Hollerieth, Vanessa; Mattes, Julian; Geffers, Robert; Raimúndez, Elba; Hasenauer, Jan; Luber, Birgit: Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines. 20 (1), 2020 mehr…
• Ebert, Karolin; Zwingenberger, Gwen; Barbaria, Elena; Keller, Simone; Heck, Corinna; Arnold, Rouven; Hollerieth, Vanessa; Mattes, Julian; Geffers, Robert; Raimúndez, Elba; Hasenauer, Jan; Luber, Birgit: Correction to: Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines. 20 (1), 2020 mehr…
• Raimúndez, Elba; Keller, Simone; Zwingenberger, Gwen; Ebert, Karolin; Hug, Sabine; Theis, Fabian J; Maier, Dieter; Luber, Birgit; Hasenauer, Jan: Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines. 16 (3), 2020 mehr…
• Ebert, Karolin; Mattes, Julian; Kunzke, Thomas; Zwingenberger, Gwen; Luber, Birgit: MET as resistance factor for afatinib therapy and motility driver in gastric cancer cells. 14 (9), 2019 mehr…
• Huber, Katharina; Kunzke, Thomas; Buck, Achim; Langer, Rupert; Luber, Birgit; Feuchtinger, Annette; Walch, Axel: Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis. 99 (10), 2019, 1535-1546 mehr…
• Keller, Simone; Zwingenberger, Gwen; Ebert, Karolin; Hasenauer, Jan; Wasmuth, Jacqueline; Maier, Dieter; Haffner, Ivonne; Schierle, Katrin; Weirich, Gregor; Luber, Birgit: Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines. 12 (4), 2018, 441-462 mehr…
• Urban, Christian; Buck, Achim; Siveke, Jens T; Lordick, Florian; Luber, Birgit; Walch, Axel; Aichler, Michaela: PAXgene fixation enables comprehensive metabolomic and proteomic analyses of tissue specimens by MALDI MSI. 1862 (1), 2018, 51-60 mehr…
• Kneissl, Julia; Hartmann, Anja; Pfarr, Nicole; Erlmeier, Franziska; Lorber, Thomas; Keller, Simone; Zwingenberger, Gwen; Weichert, Wilko; Luber, Birgit: Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines. 143 (4), 2017, 573-600 mehr…
• Keller, Simone; Kneissl, Julia; Grabher-Meier, Verena; Heindl, Stefan; Hasenauer, Jan; Maier, Dieter; Mattes, Julian; Winter, Peter; Luber, Birgit: Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis. 17 (1), 2017, 845 mehr…
• Kunzke, Thomas; Balluff, Benjamin; Feuchtinger, Annette; Buck, Achim; Langer, Rupert; Luber, Birgit; Lordick, Florian; Zitzelsberger, Horst; Aichler, Michaela; Walch, Axel: Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome. 8 (40), 2017, 68012-68025 mehr…
• Dorfer, Matthias; Kazmar, Tomá?; ?míd, Mat?j; Sing, Sanchit; Kneißl, Julia; Keller, Simone; Debeir, Olivier; Luber, Birgit; Mattes, Julian: Associating approximate paths and temporal sequences of noisy detections: Application to the recovery of spatio-temporal cancer cell trajectories. 27, 2016, 72-83 mehr…
• Feuchtinger, Annette; Stiehler, Tabitha; Jütting, Uta; Marjanovic, Goran; Luber, Birgit; Langer, Rupert; Walch, Axel: Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma. 143 (1), 2015, 1-9 mehr…
• Aichler, Michaela; Motschmann, Martin; Jütting, Uta; Luber, Birgit; Becker, Karen; Ott, Katja; Lordick, Florian; Langer, Rupert; Feith, Marcus; Siewert, Jörg Rüdiger; Walch, Axel: Epidermal growth factor receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy. 5 (16), 2014, 6620-32 mehr…
• Aichler, Michaela; Luber, Birgit; Lordick, Florian; Walch, Axel: Proteomic and metabolic prediction of response to therapy in gastric cancer. 20 (38), 2014, 13648-13657 mehr…
• Heindl, S; Eggenstein, E; Keller, S; Kneissl, J; Keller, G; Mutze, K; Rauser, S; Gasteiger, G; Drexler, I; Hapfelmeier, A; Höfler, H; Luber, B: Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines. , 2012 mehr…
• Kneissl, J; Keller, S; Lorber, T; Heindl, S; Keller, G; Drexler, I; Hapfelmeier, A; Höfler, H; Luber, B: Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines. 41 (2), 2012, 733-44 mehr…
• Heindl, S; Eggenstein, E; Keller, S; Kneissl, J; Keller, G; Mutze, K; Rauser, S; Gasteiger, G; Drexler, I; Hapfelmeier, A; Höfler, H; Luber, B: Relevance of MET activation and genetic alterations of KRAS and E-cadherin for cetuximab sensitivity of gastric cancer cell lines. 138 (5), 2012, 843-58 mehr…
• Halama, N; Michel, S; Kloor, M; Zoernig, I; Benner, A; Spille, A; Pommerencke, T; von Knebel, DM; Folprecht, G; Luber, B; Feyen, N; Martens, UM; Beckhove, P; Gnjatic, S; Schirmacher, P; Herpel, E; Weitz, J; Grabe, N; Jaeger, D: Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy. 71 (17), 2011, 5670-7 mehr…
• Luber, B; Deplazes, J; Keller, G; Walch, A; Rauser, S; Eichmann, M; Langer, R; Höfler, H; Hegewisch-Becker, S; Folprecht, G; Wöll, E; Decker, T; Endlicher, E; Lorenzen, S; Fend, F; Peschel, C; Lordick, F: Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO). 11, 2011, 509 mehr…
• Kazmar, T; Smid, M; Fuchs, M; Luber, B; Mattes, J: Learning cellular texture features in microscopic cancer cell images for automated cell-detection. 1, 2010, 49-52 mehr…
• Lordick, F; Luber, B; Lorenzen, S; Hegewisch-Becker, S; Folprecht, G; Wöll, E; Decker, T; Endlicher, E; Rothling, N; Schuster, T; Keller, G; Fend, F; Peschel, C: Cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric cancer: a phase II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). 102 (3), 2010, 500-5 mehr…
• Mutze, K; Langer, R; Becker, K; Ott, K; Novotny, A; Luber, B; Hapfelmeier, A; Göttlicher, M; Höfler, H; Keller, G: Histone Deacetylase (HDAC) 1 and 2 Expression and Chemotherapy in Gastric Cancer. 17 (12), 2010, 3336-43 mehr…
• Mateus, AR; Simões-Correia, J; Figueiredo, J; Heindl, S; Alves, CC; Suriano, G; Luber, B; Seruca, R: E-cadherin mutations and cell motility: a genotype-phenotype correlation. 315 (8), 2009, 1393-402 mehr…
• Ruseva, Z; Geiger, PX; Hutzler, P; Kotzsch, M; Luber, B; Schmitt, M; Gross, E; Reuning, U: Tumor suppressor KAI1 affects integrin alphavbeta3-mediated ovarian cancer cell adhesion, motility, and proliferation. 315 (10), 2009, 1759-71 mehr…
• Deplazes, J; Fuchs, M; Rauser, S; Genth, H; Lengyel, E; Busch, R; Luber, B: Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation. 18 (19), 2009, 3632-44 mehr…
• Fuchs, M; Hermannstädter, C; Hutzler, P; Häcker, G; Haller, F; Höfler, H; Luber, B: Deletion of exon 8 increases cisplatin-induced E-cadherin cleavage. 314 (1), 2008, 153-63 mehr…
• Aubele, M; Walch, AK; Ludyga, N; Braselmann, H; Atkinson, MJ; Luber, B; Auer, G; Tapio, S; Cooke, T; Bartlett, JM: Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients. 99 (7), 2008, 1089-95 mehr…
• Walch, A; Seidl, S; Hermannstädter, C; Rauser, S; Deplazes, J; Langer, R; von Weyhern, CH; Sarbia, M; Busch, R; Feith, M; Gillen, S; Höfler, H; Luber, B: Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer. 21 (5), 2008, 544-52 mehr…
• Bremm, A; Walch, A; Fuchs, M; Mages, J; Duyster, J; Keller, G; Hermannstädter, C; Becker, KF; Rauser, S; Langer, R; von Weyhern, CH; Höfler, H; Luber, B: Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations. 68 (3), 2008, 707-14 mehr…
• Mateus, AR; Seruca, R; Machado, JC; Keller, G; Oliveira, MJ; Suriano, G; Luber, B: EGFR regulates RhoA-GTP dependent cell motility in E-cadherin mutant cells. 16 (13), 2007, 1639-47 mehr…
• Gamboa-Dominguez, A; Seidl, S; Reyes-Gutierrez, E; Hermannstädter, C; Quintanilla-Martinez, L; Busch, R; Höfler, H; Fend, F; Luber, B: Prognostic significance of p21WAF1/CIP1, p27Kip1, p53 and E-cadherin expression in gastric cancer. 60 (7), 2007, 756-61 mehr…
• Reuning, U; Schmitt, M; Luber, B; Beck, V; Magdolen, V: Methods to analyze the effects of the urokinase system on cancer cell adhesion, proliferation, migration, and signal transduction events. 120, 2006, 427-40 mehr…
• Beck, V; Herold, H; Benge, A; Luber, B; Hutzler, P; Tschesche, H; Kessler, H; Schmitt, M; Geppert, HG; Reuning, U: ADAM15 decreases integrin alphavbeta3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion. 37 (3), 2005, 590-603 mehr…
• Gamboa-Dominguez, A; Dominguez-Fonseca, C; Chavarri-Guerra, Y; Vargas, R; Reyes-Gutierrez, E; Green, D; Quintanilla-Martinez, L; Luber, B; Busch, R; Becker, KF; Becker, I; Höfler, H; Fend, F: E-cadherin expression in sporadic gastric cancer from Mexico: exon 8 and 9 deletions are infrequent events associated with poor survival. 36 (1), 2005, 29-35 mehr…
• Fuchs, M; Hermannstädter, C; Specht, K; Knyazev, P; Ullrich, A; Rosivatz, E; Busch, R; Hutzler, P; Höfler, H; Luber, B: Effect of tumor-associated mutant E-cadherin variants with defects in exons 8 or 9 on matrix metalloproteinase 3. 202 (3), 2005, 805-13 mehr…
• Fuchs, M; Hutzler, P; Handschuh, G; Hermannstädter, C; Brunner, I; Höfler, H; Luber, B: Dynamics of cell adhesion and motility in living cells is altered by a single amino acid change in E-cadherin fused to enhanced green fluorescent protein. 59 (1), 2004, 50-61 mehr…
• Gamboa-Dominguez, A; Dominguez-Fonseca, C; Quintanilla-Martinez, L; Reyes-Gutierrez, E; Green, D; Angeles-Angeles, A; Busch, R; Hermannstädter, C; Nährig, J; Becker, KF; Becker, I; Höfler, H; Fend, F; Luber, B: Epidermal growth factor receptor expression correlates with poor survival in gastric adenocarcinoma from Mexican patients: a multivariate analysis using a standardized immunohistochemical detection system. 17 (5), 2004, 579-87 mehr…
• Fricke, E; Hermannstädter, C; Keller, G; Fuchs, M; Brunner, I; Busch, R; Höfler, H; Becker, KF; Luber, B: Effect of wild-type and mutant E-cadherin on cell proliferation and responsiveness to the chemotherapeutic agents cisplatin, etoposide, and 5-fluorouracil. 66 (2), 2004, 150-9 mehr…
• Hapke, S; Kessler, H; Luber, B; Benge, A; Hutzler, P; Höfler, H; Schmitt, M; Reuning, U: Ovarian cancer cell proliferation and motility is induced by engagement of integrin alpha(v)beta3/Vitronectin interaction. 384 (7), 2003, 1073-83 mehr…
• Fricke, E; Keller, G; Becker, I; Rosivatz, E; Schott, C; Plaschke, S; Rudelius, M; Hermannstädter, C; Busch, R; Höfler, H; Becker, KF; Luber, B: Relationship between E-cadherin gene mutation and p53 gene mutation, p53 accumulation, Bcl-2 expression and Ki-67 staining in diffuse-type gastric carcinoma. 104 (1), 2003, 60-5 mehr…
• Kremer, M; Quintanilla-Martinez, L; Fuchs, M; Gamboa-Dominguez, A; Haye, S; Kalthoff, H; Rosivatz, E; Hermannstädter, C; Busch, R; Höfler, H; Luber, B: Influence of tumor-associated E-cadherin mutations on tumorigenicity and metastasis. 24 (12), 2003, 1879-86 mehr…