2020

1.

Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020.

Muenchhoff M, Mairhofer H, Nitschko H, Grzimek-Koschewa N, Hoffmann D, Berger A, Rabenau H, Widera M, Ackermann N, Konrad R, Zange S, Graf A, Krebs S, Blum H, Sing A, Liebl B, Wölfel R, Ciesek S, Drosten C, Protzer U, Boehm S, Keppler OT.

Euro Surveill. 2020 Jun;25(24):2001057. doi: 10.2807/1560-7917.ES.2020.25.24.2001057.

PMID: 32583765 Free PMC article.

2.

Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series.

Böhmer MM, Buchholz U, Corman VM, Hoch M, Katz K, Marosevic DV, Böhm S, Woudenberg T, Ackermann N, Konrad R, Eberle U, Treis B, Dangel A, Bengs K, Fingerle V, Berger A, Hörmansdorfer S, Ippisch S, Wicklein B, Grahl A, Pörtner K, Muller N, Zeitlmann N, Boender TS, Cai W, Reich A, An der Heiden M, Rexroth U, Hamouda O, Schneider J, Veith T, Mühlemann B, Wölfel R, Antwerpen M, Walter M, Protzer U, Liebl B, Haas W, Sing A, Drosten C, Zapf A.

Lancet Infect Dis. 2020 Aug;20(8):920-928. doi: 10.1016/S1473-3099(20)30314-5. Epub 2020 May 15.

PMID: 32422201 Free PMC article.

3.

Innate immune recognition and modulation in hepatitis D virus infection.

Jung S, Altstetter SM, Protzer U.

World J Gastroenterol. 2020 Jun 7;26(21):2781-2791. doi: 10.3748/wjg.v26.i21.2781.

PMID: 32550754 Free PMC article. Review.

4.

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control.

Namineni S, O'Connor T, Faure-Dupuy S, Johansen P, Riedl T, Liu K, Xu H, Singh I, Shinde P, Li F, Pandyra A, Sharma P, Ringelhan M, Muschaweckh A, Borst K, Blank P, Lampl S, Neuhaus K, Durantel D, Farhat R, Weber A, Lenggenhager D, Kündig TM, Staeheli P, Protzer U, Wohlleber D, Holzmann B, Binder M, Breuhahn K, Assmus LM, Nattermann J, Abdullah Z, Rolland M, Dejardin E, Lang PA, Lang KS, Karin M, Lucifora J, Kalinke U, Knolle PA, Heikenwalder M.

J Hepatol. 2020 May;72(5):960-975. doi: 10.1016/j.jhep.2019.12.019. Epub 2020 Jan 15.

PMID: 31954207

5.

Clinical and Epidemiological Features of a Family Cluster of Symptomatic and Asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

Wolf GK, Glueck T, Huebner J, Muenchhoff M, Hoffmann D, French LE, Keppler OT, Protzer U.

J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):362-365. doi: 10.1093/jpids/piaa060.

PMID: 32441753 Free PMC article.

6.

Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.

Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, Schneider A, Manske K, Sperl LE, Kläger S, Küster B, Wettmarshausen J, Müller C, Laschinger M, Hartmann D, Hüser N, Perocchi F, Schmitt-Kopplin P, Hagn F, Zender L, Hornung V, Borner C, Pichlmair A, Kashkar H, Klingenspor M, Prinz M, Schreiner S, Conrad M, Jost PJ, Zischka H, Steiger K, Krönke M, Zehn D, Protzer U, Heikenwälder M, Knolle PA, Wohlleber D.

J Hepatol. 2020 Dec;73(6):1347-1359. doi: 10.1016/j.jhep.2020.06.026. Epub 2020 Jun 26.

PMID: 32598967

7.

Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice.

Michler T, Kosinska AD, Festag J, Bunse T, Su J, Ringelhan M, Imhof H, Grimm D, Steiger K, Mogler C, Heikenwalder M, Michel ML, Guzman CA, Milstein S, Sepp-Lorenzino L, Knolle P, Protzer U.

Gastroenterology. 2020 May;158(6):1762-1775.e9. doi: 10.1053/j.gastro.2020.01.032. Epub 2020 Jan 28.

PMID: 32001321

8.

Intensive Care Risk Estimation in COVID-19 Pneumonia Based on Clinical and Imaging Parameters: Experiences from the Munich Cohort.

Burian E, Jungmann F, Kaissis GA, Lohöfer FK, Spinner CD, Lahmer T, Treiber M, Dommasch M, Schneider G, Geisler F, Huber W, Protzer U, Schmid RM, Schwaiger M, Makowski MR, Braren RF.

J Clin Med. 2020 May 18;9(5):1514. doi: 10.3390/jcm9051514.

PMID: 32443442 Free PMC article.

9.

A Public Health Antibody Screening Indicates a 6-Fold Higher SARS-CoV-2 Exposure Rate than Reported Cases in Children.

Hippich M, Holthaus L, Assfalg R, Zapardiel-Gonzalo J, Kapfelsperger H, Heigermoser M, Haupt F, Ewald DA, Welzhofer TC, Marcus BA, Heck S, Koelln A, Stock J, Voss F, Secchi M, Piemonti L, de la Rosa K, Protzer U, Boehmer M, Achenbach P, Lampasona V, Bonifacio E, Ziegler AG.

Med (N Y). 2021 Feb 12;2(2):149-163.e4. doi: 10.1016/j.medj.2020.10.003. Epub 2020 Oct 29.

PMID: 33163984 Free PMC article.

10.

HDVdb: A Comprehensive Hepatitis D Virus Database.

Usman Z, Velkov S, Protzer U, Roggendorf M, Frishman D, Karimzadeh H.

Viruses. 2020 May 14;12(5):538. doi: 10.3390/v12050538.

PMID: 32422927 Free PMC article.

11.

[Strategy for university emergency room management at the beginning of an epidemic using COVID-19 as an example].

Dommasch M, Gebhardt F, Protzer U, Werner A, Schuster E, Brakemeier C, Mayer J, Feihl S, Querbach C, Braren R, Treiber M, Geisler F, Spinner CD.

Notf Rett Med. 2020 Jul 15:1-9. doi: 10.1007/s10049-020-00759-8. Online ahead of print.

PMID: 32837305 Free PMC article. Review. German.

12.

Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients.

Afridi SQ, Moeini H, Kalali B, Wettengel JM, Quitt O, Semper R, Gerhard M, Protzer U, Hoffmann D.

Braz J Microbiol. 2020 Mar;51(1):183-187. doi: 10.1007/s42770-019-00176-1. Epub 2019 Oct 26.

PMID: 31656022 Free PMC article.

13.

Two-dimensional-cultures of primary human hepatocytes allow efficient HBV infection: Old tricks still work!

Lucifora J, Michelet M, Rivoire M, Protzer U, Durantel D, Zoulim F.

J Hepatol. 2020 Aug;73(2):449-451. doi: 10.1016/j.jhep.2020.03.042. Epub 2020 May 16.

PMID: 32423632 No abstract available.

14.

Synchronised infection identifies early rate-limiting steps in the hepatitis B virus life cycle.

Chakraborty A, Ko C, Henning C, Lucko A, Harris JM, Chen F, Zhuang X, Wettengel JM, Roessler S, Protzer U, McKeating JA.

Cell Microbiol. 2020 Dec;22(12):e13250. doi: 10.1111/cmi.13250. Epub 2020 Sep 28.

PMID: 32799415

15.

Efficient and reproducible depletion of hepatitis B virus from plasma derived extracellular vesicles.

Jung S, Jacobs KFK, Shein M, Schütz AK, Mohr F, Stadler H, Stadler D, Lucko AM, Altstetter SM, Wilsch F, Deng L, Protzer U.

J Extracell Vesicles. 2020 Dec;10(2):e12040. doi: 10.1002/jev2.12040. Epub 2020 Dec 22.

PMID: 33363711 Free PMC article.

16.

Reply to the Letter of Charre et al. "Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb".

Usman Z, Velkov S, Protzer U, Roggendorf M, Frishman D, Karimzadeh H.

Viruses. 2020 Nov 9;12(11):1278. doi: 10.3390/v12111278.

PMID: 33182394 Free PMC article.

17.

Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection.

Loffredo-Verde E, Bhattacharjee S, Malo A, Festag J, Kosinska AD, Ringelhan M, Rim Sarkar S, Steiger K, Heikenwaelder M, Protzer U, Prazeres da Costa CU.

J Infect Dis. 2020 Apr 7;221(9):1448-1461. doi: 10.1093/infdis/jiz594.

PMID: 31875228

18.

A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope.

Luteijn RD, Praest P, Thiele F, Sadasivam SM, Singethan K, Drijfhout JW, Bach C, de Boer SM, Lebbink RJ, Tao S, Helfer M, Bach NC, Protzer U, Costa AI, Killian JA, Drexler I, Wiertz EJHJ.

Cells. 2020 Aug 29;9(9):1989. doi: 10.3390/cells9091989.

PMID: 32872420 Free PMC article.

19.

Noninvasive chimeric DNA profiling identifies tumor-originated HBV integrants contributing to viral antigen expression in liver cancer.

Chen W, Zhang K, Dong P, Fanning G, Tao C, Zhang H, Guo S, Wang Z, Hong Y, Yang X, Lai S, Ding H, Zhao H, Zeng C, Protzer U, Zhang D.

Hepatol Int. 2020 May;14(3):326-337. doi: 10.1007/s12072-020-10016-2. Epub 2020 Feb 25.

PMID: 32100258

20.

[Erratum to: Strategy for university emergency room management at the beginning of an epidemic using COVID-19 as an example].

Dommasch M, Gebhardt F, Protzer U, Werner A, Schuster E, Brakemeier C, Mayer J, Feihl S, Querbach C, Braren R, Treiber M, Geisler F, Spinner CD.

Notf Rett Med. 2020 Oct 20:1. doi: 10.1007/s10049-020-00797-2. Online ahead of print.

PMID: 33100899 Free PMC article. German.

21.

Global Occurrence of Clinically Relevant Hepatitis B Virus Variants as Found by Analysis of Publicly Available Sequencing Data.

Velkov S, Protzer U, Michler T.

Viruses. 2020 Nov 23;12(11):1344. doi: 10.3390/v12111344.

PMID: 33238650 Free PMC article.

22.

Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models.

Liu PJ, Harris JM, Marchi E, D'Arienzo V, Michler T, Wing PAC, Magri A, Ortega-Prieto AM, van de Klundert M, Wettengel J, Durantel D, Dorner M, Klenerman P, Protzer U, Giotis ES, McKeating JA.

Sci Rep. 2020 Aug 24;10(1):14101. doi: 10.1038/s41598-020-70865-7.

PMID: 32839523 Free PMC article.

23.

Author Correction: Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models.

Liu PJ, Harris JM, Marchi E, D'Arienzo V, Michler T, Wing PAC, Magri A, Ortega-Prieto AM, van de Klundert M, Wettengel J, Durantel D, Dorner M, Klenerman P, Protzer U, Giotis ES, McKeating JA.

Sci Rep. 2020 Nov 3;10(1):19332. doi: 10.1038/s41598-020-75963-0.

PMID: 33144658 Free PMC article.

24.

Evaluation of T-activated proteins as recall antigens to monitor Epstein-Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting.

Körber N, Behrends U, Protzer U, Bauer T.

J Transl Med. 2020 Jun 17;18(1):242. doi: 10.1186/s12967-020-02385-x.

PMID: 32552697 Free PMC article.