2011

Antigen delivery to plasmacytoid dendritic cells via BST2 induces protective T cell-mediated immunity.

Antigen delivery to plasmacytoid dendritic cells via BST2 induces protective T cell-mediated immunity.

J Immunol. 2011;186(12): 6718-25

Loschko J, Schlitzer A, Dudziak D, Drexler I, Sandholzer N, Bourquin C, Reindl W, Krug AB

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Sequential control of hepatitis B virus in a mouse model of acute, self-resolving hepatitis B.

Sequential control of hepatitis B virus in a mouse model of acute, self-resolving hepatitis B.

J Viral Hepat. 2011;18(3): 216-26

von Freyend MJ, Untergasser A, Arzberger S, Oberwinkler H, Drebber U, Schirmacher P, Protzer U

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5' Triphosphorylated Small Interfering RNAs Control Replication of Hepatitis B Virus and Induce an Interferon Response in Human Liver Cells and Mice.

5' Triphosphorylated Small Interfering RNAs Control Replication of Hepatitis B Virus and Induce an Interferon Response in Human Liver Cells and Mice.

Gastroenterology. 2011;141(2): 696-706.e3

Ebert G, Poeck H, Lucifora J, Baschuk N, Esser K, Esposito I, Hartmann G, Protzer U

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Neighbor of punc E11, a novel oncofetal marker for hepatocellular carcinoma.

Neighbor of punc E11, a novel oncofetal marker for hepatocellular carcinoma.

Int J Cancer. 2011;128(10): 2353-63

Marquardt JU, Quasdorff M, Varnholt H, Curth HM, Mesghenna S, Protzer U, Goeser T, Nierhoff D

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Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection.

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection.

J Hepatol. 2011;55(5): 996-1003

Lucifora J, Arzberger S, Durantel D, Belloni L, Strubin M, Levrero M, Zoulim F, Hantz O, Protzer U

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Interplay between modified vaccinia virus Ankara and dendritic cells: phenotypic and functional maturation of bystander dendritic cells.

Interplay between modified vaccinia virus Ankara and dendritic cells: phenotypic and functional maturation of bystander dendritic cells.

J Virol. 2011;85(11): 5532-45

Pascutti MF, Rodríguez AM, Falivene J, Giavedoni L, Drexler I, Gherardi MM

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Immune control of hepatitis B virus.

Immune control of hepatitis B virus.

Dig Dis. 2011;29(4): 423-33

Bauer T, Sprinzl M, Protzer U

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Measuring Enzymatic HIV-1 Susceptibility to Two Reverse Transcriptase Inhibitors as a Rapid and Simple Approach to HIV-1 Drug-Resistance Testing.

Measuring Enzymatic HIV-1 Susceptibility to Two Reverse Transcriptase Inhibitors as a Rapid and Simple Approach to HIV-1 Drug-Resistance Testing.

PLoS ONE. 2011;6(7): e22019

Hoffmann D, Garcia AD, Harrigan PR, Johnston IC, Nakasone T, García-Lerma JG, Heneine W

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COX-2 is not required for the development of murine chronic pancreatitis.

COX-2 is not required for the development of murine chronic pancreatitis.

Am J Physiol Gastrointest Liver Physiol. 2011;300(6): G968-75

Silva A, Weber A, Bain M, Reding T, Heikenwalder M, Sonda S, Graf R

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Hepatitis B virus impairs TLR9 expression and function in plasmacytoid dendritic cells.

Hepatitis B virus impairs TLR9 expression and function in plasmacytoid dendritic cells.

PLoS ONE. 2011;6(10): e26315

Vincent IE, Zannetti C, Lucifora J, Norder H, Protzer U, Hainaut P, Zoulim F, Tommasino M, Trepo C, Hasan U, Chemin I

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[Prophylaxis, diagnosis and therapy of hepatitis B virus infection - the German guideline].

[Prophylaxis, diagnosis and therapy of hepatitis B virus infection - the German guideline].

Z Gastroenterol. 2011;49(7): 871-930

Cornberg M, Protzer U, Petersen J, Wedemeyer H, Berg T, Jilg W, Erhardt A, Wirth S, Sarrazin C, Dollinger MM, Schirmacher P, Dathe K, Kopp IB, Zeuzem S, Gerlich WH, Manns MP, AWMF , Gerlich W, Löhr H, Protzer U, Rasenack JW, Schaefer S, Schirmacher P, Sprinzl M, Tillmann H, Treichel U, Wittekind C, Cornberg M, Döllinger M, Encke J, Geissler M, Huppe D, Niederau C, Petersen J, Tannapfel A, van Thiel I, Wasmuth HE, Van Bömmel F, Fiedler M, Geisler F, Göser T, Hinrichsen H, Kautz A, Roeb E, Sarrazin C, Schlaak J, Somasundaram R, von Weizsäcker F, Wedemeyer H, Zachoval R, Bähr M, Bechstein WO, Beckebaum S, Berg T, Jonas S, Kahl A, Kasper HU, Seehofer D, Schlitt HJ, Schmidt H, Sterneck M, Wiegand J, Wursthorn K, Heininger U, Heintges T, Höhler T, Jilg W, Kallinowski B, Radun D, Spengler U, Thimme R, Bohm S, Erhardt A, Klinker H, Mauss S, Oette M, Reiser M, Rockstroh J, Potthoff A, Kaiser R, Hofmann C, Buderus S, Henneke P, Lang T, Melter M, Schmidt-Choudhury A, Wirth S, Zimmer KG, Blum HE, Bock CT, Dienes HP, Fleig WE, Galle PR, Gerken G, Goeser T, Häussinger D, Lammert F, Lohse A, Manns MP, Neuhaus P, Ramadori G, Roeb E, Roggendorf M, Sauerbruch T, Schlitt HJ, Schmidt WE, Schmiegel W, Trautwein C, Wiedenmann B, Wittekind C, Zeuzem S, Bahr MJ, Baumgarten A, Beckebaum S, Berg T, Bock CT, Böcker U, Böker KH, Buderus S, Buggisch P, Capka E, Cornberg M, Deterding K, Dienes HP, Discher T, Döllinger M, Encke J, Erhardt A, Fiedler M, Geisler F, Geissler M, Gerlich WH, Grüngreiff K, Günther R, Heiken H, Hinrichsen H, Hofmann J, Huppe D, Jilg W, Jonas S, Jung MC, Kautz A, Kirchner G, Kittner J, Lammert F, Manns MP, Mauss S, Müller-Schilling M, Niederau C, Petersen J, Potthoff A, Probst A, Protzer U, Reiser M, Roeb E, Sarrazin C, Schiefke I, Schirmacher P, Schlaak J, Schott E, Spangenberg HC, Spengler U, Tacke F, Trowe E, Urban S, Van Bömmel F, van Thiel I, Wagner S, Wedemeyer H, Wiedenmann B, Wirth S, Wursthorn K

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Chronic liver inflammation and hepatocellular carcinoma: persistence matters.

Chronic liver inflammation and hepatocellular carcinoma: persistence matters.

Swiss Med Wkly. 2011;141(): w13197

Weber A, Boege Y, Reisinger F, Heikenwalder M

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Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction.

Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction.

J Immunol. 2011;187(6): 3186-97

Kastenmuller W, Gasteiger G, Subramanian N, Sparwasser T, Busch DH, Belkaid Y, Drexler I, Germain RN

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Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-?-dependent induction of pro-apoptotic Noxa.

Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-?-dependent induction of pro-apoptotic Noxa.

PLoS Pathog. 2011;7(6): e1002083

Eitz Ferrer P, Potthoff S, Kirschnek S, Gasteiger G, Kastenmuller W, Ludwig H, Paschen SA, Villunger A, Sutter G, Drexler I, Häcker G

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Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein.

Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein.

J Biol Chem. 2011;286(39): 33942-53

Nunziante M, Ackermann K, Dietrich K, Wolf H, Gädtke L, Gilch S, Vorberg I, Groschup M, Schätzl HM

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Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice.

Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice.

J Neural Transm. 2011;118(5): 737-45

Attems J, Ittner A, Jellinger K, Nitsch RM, Maj M, Wagner L, Götz J, Heikenwalder M

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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

Nature. 2011;479(7374): 547-51

Kang TW, Yevsa T, Woller N, Hoenicke L, Wuestefeld T, Dauch D, Hohmeyer A, Gereke M, Rudalska R, Potapova A, Iken M, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Bruder D, Manns M, Schirmacher P, Tacke F, Ott M, Luedde T, Longerich T, Kubicka S, Zender L

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Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.

PLoS ONE. 2011;6(11): e27618

Siegert S, Huang HY, Yang CY, Scarpellino L, Carrie L, Essex S, Nelson PJ, Heikenwalder M, Acha-Orbea H, Buckley CD, Marsland BJ, Zehn D, Luther SA

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The parallel universe: microRNAs and their role in chronic hepatitis, liver tissue damage and hepatocarcinogenesis.

The parallel universe: microRNAs and their role in chronic hepatitis, liver tissue damage and hepatocarcinogenesis.

Swiss Med Wkly. 2011;141(): w13287

Haybaeck J, Zeller N, Heikenwalder M

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Lymphotoxin's link to carcinogenesis: friend or foe? from lymphoid neogenesis to hepatocellular carcinoma and prostate cancer.

Lymphotoxin's link to carcinogenesis: friend or foe? from lymphoid neogenesis to hepatocellular carcinoma and prostate cancer.

Adv Exp Med Biol. 2011;691(): 231-49

Wolf MJ, Seleznik GM, Heikenwalder M

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Aerosols transmit prions to immunocompetent and immunodeficient mice.

Aerosols transmit prions to immunocompetent and immunodeficient mice.

PLoS Pathog. 2011;7(1): e1001257

Haybaeck J, Heikenwalder M, Klevenz B, Schwarz P, Margalith I, Bridel C, Mertz K, Zirdum E, Petsch B, Fuchs TJ, Stitz L, Aguzzi A

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