Selected Publications
2021
| The UFM1 Pathway Impacts HCMV US2-Mediated Degradation of HLA Class I. Schuren ABC, Boer IGJ, Bouma EM, Van de Weijer ML, Costa AI, Hubel P, Pichlmair A, Lebbink RJ, Wiertz EJHJ. Molecules. 2021 Jan 8;26(2):287. doi: 10.3390/molecules26020287. PMID: 33430125 Free PMC article. |
| Human NLRP1 is a sensor for double-stranded RNA. Bauernfried S, Scherr MJ, Pichlmair A, Duderstadt KE, Hornung V. Science. 2021 Jan 29;371(6528):eabd0811. doi: 10.1126/science.abd0811. Epub 2020 Nov 26. PMID: 33243852 |
| Lainšček D, Fink T, Forstnerič V, Hafner-Bratkovič I, Orehek S, Strmšek Ž, Manček-Keber M, Pečan P, Esih H, Malenšek Š, Aupič J, Dekleva P, Plaper T, Vidmar S, Kadunc L, Benčina M, Omersa N, Anderluh G, Pojer F, Lau K, Hacker D, Correia BE, Peterhoff D, Wagner R, Bergant V, Herrmann A, Pichlmair A, Jerala R. Vaccines (Basel). 2021 Apr 27;9(5):431. doi: 10.3390/vaccines9050431. PMID: 33925446 Free PMC article. |
| Gonzalez-Perez AC, Stempel M, Wyler E, Urban C, Piras A, Hennig T, Ganskih S, Wei Y, Heim A, Landthaler M, Pichlmair A, Dölken L, Munschauer M, Erhard F, Brinkmann MM. mBio. 2021 May 4;12(3):e02683-20. doi: 10.1128/mBio.02683-20. PMID: 33947766 Free PMC article. |
| Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Stukalov A, Girault V, Grass V, Karayel O, Bergant V, Urban C, Haas DA, Huang Y, Oubraham L, Wang A, Hamad MS, Piras A, Hansen FM, Tanzer MC, Paron I, Zinzula L, Engleitner T, Reinecke M, Lavacca TM, Ehmann R, Wölfel R, Jores J, Kuster B, Protzer U, Rad R, Ziebuhr J, Thiel V, Scaturro P, Mann M, Pichlmair A. Nature. 2021 Jun;594(7862):246-252. doi: 10.1038/s41586-021-03493-4. Epub 2021 Apr 12. PMID: 33845483 |
| Manček-Keber M, Hafner-Bratkovič I, Lainšček D, Benčina M, Govednik T, Orehek S, Plaper T, Jazbec V, Bergant V, Grass V, Pichlmair A, Jerala R. FASEB J. 2021 Jun;35(6):e21651. doi: 10.1096/fj.202100560R. PMID: 34004056 Free PMC article. |
| Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20. Stadler D, Kächele M, Jones AN, Hess J, Urban C, Schneider J, Xia Y, Oswald A, Nebioglu F, Bester R, Lasitschka F, Ringelhan M, Ko C, Chou WM, Geerlof A, van de Klundert MA, Wettengel JM, Schirmacher P, Heikenwälder M, Schreiner S, Bartenschlager R, Pichlmair A, Sattler M, Unger K, Protzer U. EMBO Rep. 2021 Jun 4;22(6):e49568. doi: 10.15252/embr.201949568. Epub 2021 May 9. PMID: 33969602 Free PMC article. |
| Human cytomegalovirus-induced host protein citrullination is crucial for viral replication. Griffante G, Gugliesi F, Pasquero S, Dell'Oste V, Biolatti M, Salinger AJ, Mondal S, Thompson PR, Weerapana E, Lebbink RJ, Soppe JA, Stamminger T, Girault V, Pichlmair A, Oroszlán G, Coen DM, De Andrea M, Landolfo S. Nat Commun. 2021 Jun 23;12(1):3910. doi: 10.1038/s41467-021-24178-6. PMID: 34162877 Free PMC article. |
| Krivega M, Stiefel CM, Karbassi S, Andersen LL, Chunduri NK, Donnelly N, Pichlmair A, Storchová Z. Commun Biol. 2021 Jul 2;4(1):831. doi: 10.1038/s42003-021-02278-9. PMID: 34215848 Free PMC article. |
| Fischer DS, Ansari M, Wagner KI, Jarosch S, Huang Y, Mayr CH, Strunz M, Lang NJ, D'Ippolito E, Hammel M, Mateyka L, Weber S, Wolff LS, Witter K, Fernandez IE, Leuschner G, Milger K, Frankenberger M, Nowak L, Heinig-Menhard K, Koch I, Stoleriu MG, Hilgendorff A, Behr J, Pichlmair A, Schubert B, Theis FJ, Busch DH, Schiller HB, Schober K. Nat Commun. 2021 Jul 26;12(1):4515. doi: 10.1038/s41467-021-24730-4. PMID: 34312385 Free PMC article. |
| Two cGAS-like receptors induce antiviral immunity in Drosophila. Holleufer A, Winther KG, Gad HH, Ai X, Chen Y, Li L, Wei Z, Deng H, Liu J, Frederiksen NA, Simonsen B, Andersen LL, Kleigrewe K, Dalskov L, Pichlmair A, Cai H, Imler JL, Hartmann R. Nature. 2021 Sep;597(7874):114-118. doi: 10.1038/s41586-021-03800-z. Epub 2021 Jul 14. PMID: 34261128 |
| Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription. Pei J, Beri NR, Zou AJ, Hubel P, Dorando HK, Bergant V, Andrews RD, Pan J, Andrews JM, Sheehan KCF, Pichlmair A, Amarasinghe GK, Brody SL, Payton JE, Leung DW. Cell Rep. 2021 Oct 12;37(2):109803. doi: 10.1016/j.celrep.2021.109803. PMID: 34644581 Free PMC article. |
2020
| Sib A, Milzarek TM, Herrmann A, Oubraham L, Müller JI, Pichlmair A, Brack-Werner R, Gulder TAM. Chembiochem. 2020 Feb 17;21(4):492-495. doi: 10.1002/cbic.201900472. Epub 2019 Nov 19. PMID: 31448469 Free PMC article. |
| Fabits M, Gonçalves Magalhães V, Chan B, Girault V, Elbasani E, Rossetti E, Saeland E, Messerle M, Pichlmair A, Lisnić VJ, Brinkmann MM. Microorganisms. 2020 May 26;8(6):790. doi: 10.3390/microorganisms8060790. PMID: 32466380 Free PMC article. |
| Persistent Innate Immune Stimulation Results in IRF3-Mediated but Caspase-Independent Cytostasis. Urban C, Welsch H, Heine K, Wüst S, Haas DA, Dächert C, Pandey A, Pichlmair A, Binder M. Viruses. 2020 Jun 11;12(6):635. doi: 10.3390/v12060635. PMID: 32545331 Free PMC article. |
| eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition. Wuerth JD, Habjan M, Kainulainen M, Berisha B, Bertheloot D, Superti-Furga G, Pichlmair A, Weber F. mBio. 2020 Jul 14;11(4):e00976-20. doi: 10.1128/mBio.00976-20. PMID: 32665273 Free PMC article. |
| Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing. Sadegh S, Matschinske J, Blumenthal DB, Galindez G, Kacprowski T, List M, Nasirigerdeh R, Oubounyt M, Pichlmair A, Rose TD, Salgado-Albarrán M, Späth J, Stukalov A, Wenke NK, Yuan K, Pauling JK, Baumbach J. Nat Commun. 2020 Jul 14;11(1):3518. doi: 10.1038/s41467-020-17189-2. PMID: 32665542 Free PMC article. |
| Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing. Zecha J, Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, Schnatbaum K, Michler T, Pichlmair A, Ludwig C, Kuster B. Mol Cell Proteomics. 2020 Sep;19(9):1503-1522. doi: 10.1074/mcp.RA120.002164. Epub 2020 Jun 26. PMID: 32591346 Free PMC article. |
| System-Based Approaches to Delineate the Antiviral Innate Immune Landscape. Krey K, Babnis AW, Pichlmair A. Viruses. 2020 Oct 21;12(10):1196. doi: 10.3390/v12101196. PMID: 33096788 Free PMC article. Review. |
| Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, Schneider A, Manske K, Sperl LE, Kläger S, Küster B, Wettmarshausen J, Müller C, Laschinger M, Hartmann D, Hüser N, Perocchi F, Schmitt-Kopplin P, Hagn F, Zender L, Hornung V, Borner C, Pichlmair A, Kashkar H, Klingenspor M, Prinz M, Schreiner S, Conrad M, Jost PJ, Zischka H, Steiger K, Krönke M, Zehn D, Protzer U, Heikenwälder M, Knolle PA, Wohlleber D. J Hepatol. 2020 Dec;73(6):1347-1359. doi: 10.1016/j.jhep.2020.06.026. Epub 2020 Jun 26. PMID: 32598967 |
| Human NLRP1 is a sensor for double-stranded RNA. Bauernfried S, Scherr MJ, Pichlmair A, Duderstadt KE, Hornung V. Science. 2021 Jan 29;371(6528):eabd0811. doi: 10.1126/science.abd0811. Epub 2020 Nov 26. PMID: 33243852 |
2019
| Oxeiptosis: a discreet way to respond to radicals. Scaturro P, Pichlmair A. Curr Opin Immunol. 2019 Feb;56:37-43. doi: 10.1016/j.coi.2018.10.006. Epub 2018 Oct 18. PMID: 30342374 Review. |
| Hubel P, Urban C, Bergant V, Schneider WM, Knauer B, Stukalov A, Scaturro P, Mann A, Brunotte L, Hoffmann HH, Schoggins JW, Schwemmle M, Mann M, Rice CM, Pichlmair A. Nat Immunol. 2019 Apr;20(4):493-502. doi: 10.1038/s41590-019-0323-3. Epub 2019 Mar 4. PMID: 30833792 |
| Płaszczyca A, Scaturro P, Neufeldt CJ, Cortese M, Cerikan B, Ferla S, Brancale A, Pichlmair A, Bartenschlager R. PLoS Pathog. 2019 May 9;15(5):e1007736. doi: 10.1371/journal.ppat.1007736. eCollection 2019 May. PMID: 31071189 Free PMC article. |
| Chasing Intracellular Zika Virus Using Proteomics. Scaturro P, Kastner AL, Pichlmair A. Viruses. 2019 Sep 19;11(9):878. doi: 10.3390/v11090878. PMID: 31546825 Free PMC article. Review. |
| Neufeldt CJ, Cortese M, Scaturro P, Cerikan B, Wideman JG, Tabata K, Moraes T, Oleksiuk O, Pichlmair A, Bartenschlager R. Nat Microbiol. 2019 Dec;4(12):2416-2429. doi: 10.1038/s41564-019-0586-3. Epub 2019 Oct 21. PMID: 31636417 Free PMC article. |
| The alternative cap-binding complex is required for antiviral defense in vivo. Gebhardt A, Bergant V, Schnepf D, Moser M, Meiler A, Togbe D, Mackowiak C, Reinert LS, Paludan SR, Ryffel B, Stukalov A, Staeheli P, Pichlmair A. PLoS Pathog. 2019 Dec 19;15(12):e1008155. doi: 10.1371/journal.ppat.1008155. eCollection 2019 Dec. PMID: 31856218 Free PMC article. |
| Sib A, Milzarek TM, Herrmann A, Oubraham L, Müller JI, Pichlmair A, Brack-Werner R, Gulder TAM. Chembiochem. 2020 Feb 17;21(4):492-495. doi: 10.1002/cbic.201900472. Epub 2019 Nov 19. PMID: 31448469 Free PMC article. |
| Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing. Sadegh S, Matschinske J, Blumenthal DB, Galindez G, Kacprowski T, List M, Nasirigerdeh R, Oubounyt M, Pichlmair A, Rose TD, Salgado-Albarrán M, Späth J, Stukalov A, Wenke NK, Yuan K, Pauling JK, Baumbach J. Nat Commun. 2020 Jul 14;11(1):3518. doi: 10.1038/s41467-020-17189-2. PMID: 32665542 Free PMC article. |
| Human cytomegalovirus-induced host protein citrullination is crucial for viral replication. Griffante G, Gugliesi F, Pasquero S, Dell'Oste V, Biolatti M, Salinger AJ, Mondal S, Thompson PR, Weerapana E, Lebbink RJ, Soppe JA, Stamminger T, Girault V, Pichlmair A, Oroszlán G, Coen DM, De Andrea M, Landolfo S. Nat Commun. 2021 Jun 23;12(1):3910. doi: 10.1038/s41467-021-24178-6. PMID: 34162877 Free PMC article. |
| Fischer DS, Ansari M, Wagner KI, Jarosch S, Huang Y, Mayr CH, Strunz M, Lang NJ, D'Ippolito E, Hammel M, Mateyka L, Weber S, Wolff LS, Witter K, Fernandez IE, Leuschner G, Milger K, Frankenberger M, Nowak L, Heinig-Menhard K, Koch I, Stoleriu MG, Hilgendorff A, Behr J, Pichlmair A, Schubert B, Theis FJ, Busch DH, Schiller HB, Schober K. Nat Commun. 2021 Jul 26;12(1):4515. doi: 10.1038/s41467-021-24730-4. PMID: 34312385 Free PMC article. |
2018
| Viperin Targets Flavivirus Virulence by Inducing Assembly of Noninfectious Capsid Particles. Vonderstein K, Nilsson E, Hubel P, Nygård Skalman L, Upadhyay A, Pasto J, Pichlmair A, Lundmark R, Överby AK. J Virol. 2017 Dec 14;92(1):e01751-17. doi: 10.1128/JVI.01751-17. Print 2018 Jan 1. PMID: 29046456 Free PMC article. |
| Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, Pichlmair A. Nat Immunol. 2018 Feb;19(2):130-140. doi: 10.1038/s41590-017-0013-y. Epub 2017 Dec 18. PMID: 29255269 Free PMC article. |
| Viral targeting of TFIIB impairs de novo polymerase II recruitment and affects antiviral immunity. Haas DA, Meiler A, Geiger K, Vogt C, Preuss E, Kochs G, Pichlmair A. PLoS Pathog. 2018 Apr 30;14(4):e1006980. doi: 10.1371/journal.ppat.1006980. eCollection 2018 Apr. PMID: 29709033 Free PMC article. |
| Oxeiptosis-a cell death pathway to mitigate damage caused by radicals. Scaturro P, Pichlmair A. Cell Death Differ. 2018 Jul;25(7):1191-1193. doi: 10.1038/s41418-018-0134-3. PMID: 29844568 Free PMC article. No abstract available. |
| An orthogonal proteomic survey uncovers novel Zika virus host factors. Scaturro P, Stukalov A, Haas DA, Cortese M, Draganova K, Płaszczyca A, Bartenschlager R, Götz M, Pichlmair A. Nature. 2018 Sep;561(7722):253-257. doi: 10.1038/s41586-018-0484-5. Epub 2018 Sep 3. PMID: 30177828 |
| Wuerth JD, Habjan M, Wulle J, Superti-Furga G, Pichlmair A, Weber F. J Virol. 2018 Nov 12;92(23):e01202-18. doi: 10.1128/JVI.01202-18. Print 2018 Dec 1. PMID: 30232186 Free PMC article. |
| Oxeiptosis: a discreet way to respond to radicals. Scaturro P, Pichlmair A. Curr Opin Immunol. 2019 Feb;56:37-43. doi: 10.1016/j.coi.2018.10.006. Epub 2018 Oct 18. PMID: 30342374 Review. |
2017
Vonderstein K, Nilsson E, Hubel P, Nygård Skalman L, Upadhyay A, Pasto J, Pichlmair A, Lundmark R, Överby AK.; Viperin targets flavivirus virulence by inducing assembly of non-infectious capsid particles. J Virol. 2017 Oct 18. pii: JVI.01751-17
Goonawardane N, Gebhardt A, Bartlett C, Pichlmair A, Harris M. Phosphorylation of Serine 225 in Hepatitis C Virus NS5A Regulates Protein-Protein Interactions. J Virol. 2017 Aug 10;91(17).
Brady G, Haas DA, Farrell PJ, Pichlmair A, Bowie AG.Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation. J Virol. 2017 Jul 12;91(15). pii: e00545-17.
Gebhardt A, Laudenbarch B, Pichlmair A; Discrimination of self and non-self ribonucleic acids.: J Interferon Cytokine Res. 2017 May;37(5):184-197.
Abbas YM, Laudenbach BT, Martínez-Montero S, Cencic R, Habjan M, Pichlmair A., Damha MJ, Pelletier J, Nagar B.; Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations. Proc Natl Acad Sci. 2017 Mar 14;114(11):E2106-E2115.
Willemsen J, Wicht O, Wolanski JC, Baur N, Bastian S, Haas DA, Matula P, Knapp B, Meyniel-Schicklin L, Wang C, Bartenschlager R, Lohmann V, Rohr K, Erfle H, Kaderali L, Marcotrigiano J, Pichlmair A, Binder M.; Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening. Mol Cell. 2017 Feb 2;65(3):403-415.e8. doi: 10.1016/j.molcel.2016.12.021.
2016
Mazouzi A, Stukalov A, Müller AC, Chen D, Wiedner M, Prochazkova J, Chiang SC, Schuster M, Breitwieser FP, Pichlmair A, El-Khamisy SF, Bock C, Kralovics R, Colinge J, Bennett KL, Loizou JI.; A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN. Cell Reports, 2016 Apr 14. doi: 10.1016/j.celrep.2016.03.077.
2015
Stukalov A, Pichlmair A.; Gambling with Flu: "All in" to Maximize Reward. Cell Host Microbe, 2015 Dec 9;18(6):643-5.
Gebhardt A., Habjan M., Benda C., Meiler A., Haas D.A., Hein M.Y., Mann A., Mann M., Habermann B. and Pichlmair A.; mRNA export through an additional cap-binding complex consisting of NCBP1 and -3. Nature Communications, 2015, Sep 18;6:8192. doi: 10.1038/ncomms9192.
Heinz L.X., Baumann C.L., Köberlin M.S., Snijder B., Gawish R., Shui G., Sharif O., Aspalter I.M., Müller A.C., Kandasamy R.K., Breitwieser F.P., Pichlmair A., Bruckner M., Rebsamen M., Blüml S., Karonitsch T., Fauster A., Colinge J., Bennett K.L., Knapp S., Wenk M.R., Superti-Furga G.; The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity. Cell Reports, 2015, Jun 30;11(12):1919-28.
Brady G., Haas D.A., Farrell P.J., Pichlmair A., Bowie A.G.; Poxvirus protein MC132 from Molluscum Contagiosum Virus inhibits NFκB activation by targeting p65 for degradation. J Virol, 2015, Aug;89(16):8406-15.
Habjan M., Pichlmair A.; Cytoplasmic sensing of viral RNA; Curr op. Virology, 2015, Apr;11:31-37.
2014
Eberle C.A., Zayas M., Stukalov A., Pichlmair A., Alvisi G., Müller A.C., Bennett K.L., Bartenschlager R., Superti-Furga G.; The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production. Virology, 2014, Aug;462-463:34-41.
Upadhyay A.S., Vonderstein K., Pichlmair A., Stehling O., Bennett K.L., Dobler G., Guo J.T., Superti-Furga G., Lill R., Overby A.K., Weber F.; Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity. Cell Microbiol, 2014, Jun;16(6):834-48.
Kainulainen M., Habjan M., Hubel P., Busch L., Lau S., Colinge J., Superti-Furga G., Pichlmair A., Weber F.; Virulence factor NSs of Rift Valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH. J Virol, 2014, Mar;88(6):3464-73.
Liehl P., Zuzarte-Luís V., Chan J., Zillinger T., Baptista F., Carapau D., Konert M., Hanson K.K., Carret C., Lassnig C., Müller M., Kalinke U., Saeed M., Chora A.F., Golenbock D.T., Strobl B., Prudêncio M., Coelho L.P., Kappe S.H., Superti-Furga G., Pichlmair A., Vigário A.M., Rice C.M., Fitzgerald K.A., Barchet W., Mota M.M.; Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection. Nat Med, 2014, Jan;20(1):47-53.
2013
Habjan M, Hubel P, Lacerda L, Benda C, Holze C, Eberl CH, Mann A, Kindler E, Gil-Cruz C, Ziebuhr J, Thiel V, Pichlmair A. Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA. PLoS Pathog, 2013, Oct;9(10):e1003663.
Abbas, YM., Pichlmair, A., Górna, MW., Superti-Furga, G., Nagar, B.; Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins.; Nature, 2013, Feb 7;494(7435).60-4.
2012
Pichlmair, A., Kandasamy, K., Alvisi, G., Mulhern, O., Sacco, R., Habjan, M., Binder, M., Stefanovic, A., Eberle, C.A., Goncalves, A., Bürckstümmer, T., Müller, A., Fauster, A., Holze, A., Lindsten, K., Goodbourn, S., Kochs, G., Weber, F., Bartenschlager, R., Bowie, A.G., Bennett, K.L., Colinge, J. and Superti-Furga. G; Viral immune modulators perturb the human molecular network by common and unique strategies.; Nature, 2012, Jul 26;487(7408):486-90.
2011
Pichlmair, A., Lassnig. C., Eberle C.A., Górna M.W., Baumann C.L., Burkard T.R., Bürckstümmer T., Stefanovic A., Krieger S., Bennett K.L., Rülicke T., Weber F., Colinge J., Müller M., Superti-Furga G.; IFIT1 is an antiviral protein that recognizes 5’-triphosphate RNA.; Nat Immunol, 2011, Jun 5;12(7):624-30.
2010
Baumann, C.L., Aspalter, I.M., Sharif, O., Pichlmair. A., Blüml, S., Grebien, F., Bruckner, M., Pasierbek, P., Aumayr, K., Planyavsky, M., Bennett, K.L., Colinge, J., Knapp, S., Superti-Furga, G.; CD14 is a coreceptor of Toll-like receptors 7 and 9.; J Exp Med, 2010, Nov 22;207(12):2689-701.
Pichlmair, A., Habjan, M., Unger, H., Weber, F.; Virus-Like Particles Expressing the Nucleocapsid Gene as an Efficient Vaccine Against Rift Valley Fever Virus.; Vector-Borne and Zoonotic Diseases, 2010, Oct;10(7):701-3
Schulz, O., Pichlmair, A., Rehwinkel, J., Rogers, NC., Scheuner, D., Kato, H., Takeuchi, O., Akira, S., Kaufman, RJ., Reis e Sousa, C.; Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity.; Cell Host Microbe, 2010, May 20;7(5):354-61.
Rehwinkel, J., Tan, CP., Goubau, D., Schulz, O., Pichlmair, A., Bier, K., Robb, N., Vreede, F., Barclay, W., Fodor, E., Reis e Sousa, C.; RIG-I detects viral genomic RNA during negative-strand RNA virus infection.; Cell, 2010, Feb 5;140(3):397-408.
2009
Pichlmair, A., Schulz, O., Tan, CP., Rehwinkel, J., Kato, H., Takeuchi, O., Akira, S., Way, M., Schiavo, G., Reis e Sousa, C.; Activation of MDA5 requires higher-order RNA structures generated during virus infection.; J Virol, 2009, Oct;83(20):10761-9.
Pichlmair, A.*, Habjan, M.*, Elliott, RM., Overby, AK., Glatter, T., Gstaiger, M., Superti-Furga, G., Unger, H., Weber, F.; NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase; J Virol, 2009, May; 83(9):4365-75. *contributed equally
2008
Habjan, M., Andersson, I., Klingström, J., Schümann, M., Martin, A., Zimmermann, P., Wagner, V., Pichlmair, A., Schneider, U., Mühlberger, E., Mirazimi, A., Weber, F.; Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction; PLoS One, 2008, Apr 30; 3(4):e2032.
2007
Pichlmair, A. and Reis e Sousa, C.; Innate recognition of viruses; Immunity, 2007, Sep 21;27(3): 370-383
Pichlmair, A., Diebold, S.S., Gschmeissner, S., Takeuchi, Y., Ikeda, Y., Collins, M.K. and Reis e Sousa, C.; Tubulovesicular Structures within Vesicular Stomatitis Virus G Protein-Pseudotyped Lentiviral Vector Preparations Carry DNA and Stimulate Antiviral Responses via Toll-Like Receptor 9; J Virol, 2007, Jan; 81(2): 539-47
2006
Pichlmair, A., Schulz, O., Tan, C.P., Näslund, T.I., Liljeström, P., Weber, F. and Reis e Sousa, C.; RIG-I-mediated antiviral responses to single stranded RNA bearing 5’ phosphates; Science, 2006, Nov; 314: 997-1001
2005
Spiegel, M., Pichlmair, A., Martínez-Sobrido, L., Cros, J., García-Sastre, A., Haller, O. and Weber, F.: Inhibition of interferon-beta induction by SARS coronavirus suggests a two-step model for activation of interferon regulatory factor 3; J Virol, 2005, Feb; 79(4): 2079-86
2004
Pichlmair, A., Buse, J., Jennings, S., Haller, O., Kochs, G. and Staeheli, P.: Thogoto Virus lacking interferon – antagonistic factor ML is strongly attenuated in Mx1-positive but not Mx1-negative mice; J Virol, 2004, Oct; 78(20): 11422-4