Laboratories

Biomarkers

In the Biomarkers Group, we study preclinical models of disease with label-free MSOT imaging to develop working pipelines for in vivo detection and quantification of biomarkers, such as lipid content, blood perfusion, and tissue oxygenation. (more)

Cell Engineering

The use of proteins, nucleic acids or complete cells as genetically encodable and engineerable molecular tools becomes increasingly important. One of the most prolific areas is the construction of labels and sensors for in vivo and in situ imaging (e.g. fluorescent protein based). ...(more)

Clinical Bioengineering

The Clinical Bioengineering Group innovates optoacoustic (photoacoustic) systems and theory for reaching unprecedent imaging ability in preclinical and clinical anatomical, physiological and molecular imaging applications...(more)

Computation and Machine Learning

The Computation and Machine Learning Group develops imaging technology using optical and optoacoustic methods, with a focus on development of novel imaging reconstruction algorithms. (more)

Fluorescence Imaging

The Laboratory develops advanced fluorescence imaging methods for pre-clinical and clinical imaging, leading in 2011 to the first clinical translation of a targeted fluorescent agent for optical molecular imaging of patients. Focus is on the development of quantitative, real-time and tomographic methods that go well beyond conventional “photographic” fluorescence image...(more)

Optoacoustic Endoscopy

The Laboratory for Clinical Optoacoustics innovates optoacoustic (photoacoustic) systems and theory for reaching unprecedent imaging ability in preclinical and clinical anatomical, physiological and molecular imaging applications...(more)

Optoacoustic Mesoscopy

Our group conceives, designs and develops multispectral optoacoustic technology that allows performing non-invasive anatomical, functional and molecular optical imaging of the skin in the clinics...(more)

Sensors

Our research innovates methods for high resolution radio-frequency absorption imaging in tissues. Overcoming the depth limitation of optoacoustic (photoacoustic) systems, thermo-acoustics can be employed to interrogate deeper in tissues...(more)

Translational Optoacoustics

Our group focuses on developing technology and applications on the combination of optical and optoacoustic microscopy in order to deliver contrast and imaging abilities not available in optical microscopes today. (more).

Biology Core Facility

The group is centered around provision and development of cell lines and animal models for optoacoustic imaging. Our portfolio includes transgenic cancer cell lines stably expressing iRPF720 and tyrosinase (both labels provide good contrast in optoacoustic imaging), systems for retroviral gene transfer and various chemical labels for primary cells....(more)