2019

Shaping the diversity of Th2 cell responses in epithelial tissues and its potential for allergy treatment.

Shaping the diversity of Th2 cell responses in epithelial tissues and its potential for allergy treatment.

Eur J Immunol. 2019;49(9): 1321-1333

Matthias J, Zielinski CE

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Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection.

Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection.

J Infect Dis. 2019;():

Loffredo-Verde E, Bhattacharjee S, Malo A, Festag J, Kosinska AD, Ringelhan M, Rim Sarkar S, Steiger K, Heikenwaelder M, Protzer U, Prazeres da Costa CU

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Sodium chloride is an ionic checkpoint for human TH2 cells and shapes the atopic skin microenvironment.

Sodium chloride is an ionic checkpoint for human TH2 cells and shapes the atopic skin microenvironment.

Sci Transl Med. 2019;11(480):

Matthias J, Maul J, Noster R, Meinl H, Chao YY, Gerstenberg H, Jeschke F, Gasparoni G, Welle A, Walter J, Nordström K, Eberhardt K, Renisch D, Donakonda S, Knolle P, Soll D, Grabbe S, Garzorz-Stark N, Eyerich K, Biedermann T, Baumjohann D, Zielinski CE

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Comparative Analysis of the Antiviral Effects Mediated by Type I and III Interferons in Hepatitis B Virus-Infected Hepatocytes.

Comparative Analysis of the Antiviral Effects Mediated by Type I and III Interferons in Hepatitis B Virus-Infected Hepatocytes.

J Infect Dis. 2019;220(4): 567-577

Bockmann JH, Stadler D, Xia Y, Ko C, Wettengel JM, Schulze Zur Wiesch J, Dandri M, Protzer U

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Estimation of liver fibrosis by noncommercial serum markers in comparison with transient elastography in patients with chronic hepatitis C virus infection receiving direct-acting antiviral treatment.

Estimation of liver fibrosis by noncommercial serum markers in comparison with transient elastography in patients with chronic hepatitis C virus infection receiving direct-acting antiviral treatment.

J Viral Hepat. 2019;26(2): 224-230

Knop V, Hofmann WP, Buggisch P, Klinker H, Mauss S, Günther R, Hinrichsen H, Hüppe D, Pfeiffer-Vornkahl H, Simon KG, Berg T, Manns MP, Friedrich-Rust M, German Hepatitis C-Registry , Pathil A, Zimmermann T, Heyne R, Goeser T, Ullrich R, Möller H, Geier A, Lutz T, Busch H, Gerken G, Naumann U, Antoni C, Cordes C, John C, Roessle M, Christensen S, Müller T, Hillenbrand H, Herzer K, Jäger H, Felten G, Stoehr A, Scholten S, Kuhn M, Erren P, Cornberg M, Niederau C, Protzer U, Sarrazin C, Schirmacher P, Wedemeyer H, Zeuzem S

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Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection.

Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection.

Sci Rep. 2019;9(1):

Kosinska AD, Moeed A, Kallin N, Festag J, Su J, Steiger K, Michel ML, Protzer U, Knolle PA

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Targeting Innate and Adaptive Immune Responses to Cure Chronic HBV Infection.

Targeting Innate and Adaptive Immune Responses to Cure Chronic HBV Infection.

Gastroenterology. 2019;156(2): 325-337

Gehring A, Protzer U

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Revisiting Hepatitis B Virus: Challenges of Curative Therapies.

Revisiting Hepatitis B Virus: Challenges of Curative Therapies.

J Virol. 2019;93(20):

Hu J, Protzer U, Siddiqui A

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PASylated interferon ? efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice.

PASylated interferon ? efficiently suppresses hepatitis B virus and induces anti-HBs seroconversion in HBV-transgenic mice.

Antiviral Res. 2019;161(): 134-143

Xia Y, Schlapschy M, Morath V, Roeder N, Vogt EI, Stadler D, Cheng X, Dittmer U, Sutter K, Heikenwälder M, Skerra A, Protzer U

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Towards curative therapy of chronic viral hepatitis.

Towards curative therapy of chronic viral hepatitis.

Z Gastroenterol. 2019;57(1): 61-73

Bartenschlager R, Urban S, Protzer U

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A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.

A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.

Life Sci Alliance. 2019;2(2):

Wing PA, Davenne T, Wettengel J, Lai AG, Zhuang X, Chakraborty A, D'Arienzo V, Kramer C, Ko C, Harris JM, Schreiner S, Higgs M, Roessler S, Parish JL, Protzer U, Balfe P, Rehwinkel J, McKeating JA

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Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients.

Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients.

Braz J Microbiol. 2019;():

Afridi SQ, Moeini H, Kalali B, Wettengel JM, Quitt O, Semper R, Gerhard M, Protzer U, Hoffmann D

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A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection.

A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection.

Antimicrob Agents Chemother. 2019;64(1):

Ko C, Bester R, Zhou X, Xu Z, Blossey C, Sacherl J, Vondran FWR, Gao L, Protzer U

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Evaluation of a Fully Human, Hepatitis B Virus-Specific Chimeric Antigen Receptor in an Immunocompetent Mouse Model.

Evaluation of a Fully Human, Hepatitis B Virus-Specific Chimeric Antigen Receptor in an Immunocompetent Mouse Model.

Mol Ther. 2019;27(5): 947-959

Festag MM, Festag J, Fräßle SP, Asen T, Sacherl J, Schreiber S, Mück-Häusl MA, Busch DH, Wisskirchen K, Protzer U

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A PCR assay to quantify patterns of HBV transcription.

A PCR assay to quantify patterns of HBV transcription.

J Gen Virol. 2019;():

D'Arienzo V, Magri A, Harris JM, Wing PAC, Ko C, Rubio CO, Revill PA, Protzer U, Balfe P, McKeating JA

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Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level.

Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level.

Gastroenterology. 2019;156(6): 1820-1833

Karimzadeh H, Kiraithe MM, Oberhardt V, Salimi Alizei E, Bockmann J, Schulze Zur Wiesch J, Budeus B, Hoffmann D, Wedemeyer H, Cornberg M, Krawczyk A, Rashidi-Alavijeh J, Rodríguez-Frías F, Casillas R, Buti M, Smedile A, Alavian SM, Heinold A, Emmerich F, Panning M, Gostick E, Price DA, Timm J, Hofmann M, Raziorrouh B, Thimme R, Protzer U, Roggendorf M, Neumann-Haefelin C

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Oxeiptosis: a discreet way to respond to radicals.

Oxeiptosis: a discreet way to respond to radicals.

Curr Opin Immunol. 2019;56(): 37-43

Scaturro P, Pichlmair A

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Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention.

Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention.

Cancer Cell. 2019;36(3): 250-267.e9

O'Connor T, Zhou X, Kosla J, Adili A, Garcia Beccaria M, Kotsiliti E, Pfister D, Johlke AL, Sinha A, Sankowski R, Schick M, Lewis R, Dokalis N, Seubert B, Höchst B, Inverso D, Heide D, Zhang W, Weihrich P, Manske K, Wohlleber D, Anton M, Hoellein A, Seleznik G, Bremer J, Bleul S, Augustin HG, Scherer F, Koedel U, Weber A, Protzer U, Förster R, Wirth T, Aguzzi A, Meissner F, Prinz M, Baumann B, Höpken UE, Knolle PA, von Baumgarten L, Keller U, Heikenwälder M

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Meeting the Challenges of High-Dimensional Single-Cell Data Analysis in Immunology.

Meeting the Challenges of High-Dimensional Single-Cell Data Analysis in Immunology.

Front Immunol. 2019;10():

Palit S, Heuser C, de Almeida GP, Theis FJ, Zielinski CE

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T cell receptor grafting allows virological control of Hepatitis B virus infection.

T cell receptor grafting allows virological control of Hepatitis B virus infection.

J Clin Invest. 2019;129(7): 2932-2945

Wisskirchen K, Kah J, Malo A, Asen T, Volz T, Allweiss L, Wettengel JM, Lütgehetmann M, Urban S, Bauer T, Dandri M, Protzer U

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