Optoacoustic Endoscopy

The Laboratory for Optoacoustic Endoscopy researches (multi-spectral) optoacoustic imaging technology geared towards clinical applications. Multi-Spectral Optoacoustic Tomography (MSOT) is a novel and powerful imaging modality pioneered at IBMI which offers high-resolution optical imaging through several millimeters to centimeters of tissue. While optical imaging is typically limited by photon scattering, resulting in image blurring, the unprecedented performance of MSOT breaks through the traditional barriers of optical imaging and microscopy (e.g. Ntziachristos V. et al., Nature Methods 7(8), 2010) and has already enabled novel insights into functional, molecular and dynamic parameters in biological and medical imaging (e.g. Herzog E., Radiology 263(2), 2012).

Relevant publications

Taruttis A., Timmermans A.C., Wouters P.C.,Kacprowicz M., Gooitzen M van Dam, Ntziachristos V. Optoacoustic Imaging of Human Vasculature: Feasibility by Using a Handheld Probe Radiology, Vol 281, Issue 1, 2016

Dima A., Ntziachristos V. In-vivo handheld optoacoustic tomography of the human thyroid Photoacoustics, Volume 4, issue 2, 2016

Buehler A., Kacprowicz M., Taruttis A.,  Ntziachristos V. Real-time handheld multispectral optoacoustic imaging Optics Letters, Vol. 38, Issue 9, pp. 1404-1406 (2013)

Dima A., Ntziachristos V. Non-invasive carotid imaging using optoacoustic tomography Optics Express, Vol. 20, Issue 22, pp. 25044-25057 (2012)

Razansky D, Buehler A, Ntziachristos V. Volumetric real-time multispectral optoacoustic tomography of biomarkers Nat Protoc, 6(8);1121-9 (2011)